Submit Your Article CMED MEACR meeting
An official publication of the Middle-Eastern Association for Cancer Research
Clinical Cancer Investigation Journal
ISSN Print: 2278-1668, Online: 2278-0513
ARTICLE
Year: 2015   |   Volume: 4   |   Issue: 2   |   Page: 206-210     View issue

Analysis of bone metastasis in head and neck squamous cell carcinoma: Experience of a regional cancer center


, , , , ,
Abstract

Background: Bone metastasis is a rare occurrence in head and neck squamous cell carcinoma (HNSCC). This retrospective study was performed to analyze the frequency and patterns of skeletal metastasis in HNSCC. Materials and Methods : We analyzed records of 8326 HNSCC patients attending our oncology outpatient department from January 2000 to December 2013. All statistical calculations were performed using MedCalc software for windows, version 12.5.0 (Osterd, Belgium). Results : Bone metastasis was found in 25 patients (0.3% of total HNSCC patients, nasopharynx excluded). 10 patients (0.66%) of carcinoma tonsil had skeletal metastasis. The patients of younger age groups had higher frequency of bone metastasis; 1.56% patients of age group 20-29 years while 0.26% patients of 60-69 years age group had skeletal metastasis (P < 0.001). However, no patient of >70 years age was found to have bone metastasis. Most common site of metastasis was spine (56%) followed by pelvis (32%). Isolated involvement of a single bony site was present in 64% of the metastatic cases. Conclusion: Bone metastasis though very rare, should be considered for evaluation in patients of HNSCC especially in younger patients.

Cite this article
Vancouver
Kapoor A, Kalwar A, Narayan S, Kumar N, Singhal M, Kumar H. Analysis of bone metastasis in head and neck squamous cell carcinoma: Experience of a regional cancer center. Clin Cancer Investig J. 2015;4(2):206-10. https://doi.org/10.4103/2278-0513.148916
APA
Kapoor, A., Kalwar, A., Narayan, S., Kumar, N., Singhal, M., & Kumar, H. (2015). Analysis of bone metastasis in head and neck squamous cell carcinoma: Experience of a regional cancer center. Clinical Cancer Investigation Journal, 4(2), 206-210. https://doi.org/10.4103/2278-0513.148916

© Clinical Cancer Investigation Journal
Online since 01 December, 2011
Creative Commons License 
ISSN Print: 2278-1668, Online: 2278-0513