Clinical Cancer Investigation Journal

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 4  |  Issue : 5  |  Page : 617--620

A comprehensive study of prostate pathology in correlation with prostate-specific antigen levels: An Indian study


Bangalore Ramalingiah Vani1, Deepak Kumar1, Burugina Nagaraj Sharath2, Venkataramappa Srinivasa Murthy1, Kempula Geethamala1 
1 Department of Pathology, ESIC Medical College and PGIMSR, Bengaluru, Karnataka, India
2 Department of Community Medicine, ESIC Medical College and PGIMSR, Bengaluru, Karnataka, India

Correspondence Address:
Bangalore Ramalingiah Vani
Department of Pathology, ESIC Medical College and PGIMSR, Rajaji Nagar, Bengaluru - 560 010, Karnataka, India.
India

Background: Diseases are primarily affecting the prostate gland ranged from inflammation to hyperplasia to malignant tumors. Carcinoma of the prostate is most common nonskin cancer in the west and the second leading cause of cancer death among men. Gleason's microscopic grading is a paramount feature and with prostate-specific antigen (PSA) are important for diagnosis, management, and prognosis of carcinoma. Objectives: The objectives were to evaluate the patterns of prevalence of prostatic lesions among the insured persons of the model hospital and to correlate histology with respect to serum PSA levels. Materials and Methods: Clinicopathological study of prostatic biopsies was conducted over a period of 1-year with emphasis on Gleason's grading and correlation of the same with PSA levels. Results: Individuals with PSA >10 had 18 times more chance of being biopsy positive in comparison to PSA <10. Conclusion: Confirmation for malignancy/screening in high-risk people is needed when PSA value is more than 4 since sensitivity is 100%, rather than PSA more than 10.


How to cite this article:
Vani BR, Kumar D, Sharath BN, Murthy VS, Geethamala K. A comprehensive study of prostate pathology in correlation with prostate-specific antigen levels: An Indian study.Clin Cancer Investig J 2015;4:617-620


How to cite this URL:
Vani BR, Kumar D, Sharath BN, Murthy VS, Geethamala K. A comprehensive study of prostate pathology in correlation with prostate-specific antigen levels: An Indian study. Clin Cancer Investig J [serial online] 2015 [cited 2021 Apr 21 ];4:617-620
Available from: https://www.ccij-online.org/article.asp?issn=2278-0513;year=2015;volume=4;issue=5;spage=617;epage=620;aulast=Vani;type=0