Clinical Cancer Investigation Journal

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 4  |  Issue : 5  |  Page : 595--602

Color Doppler ultrasonography in oral squamous cell carcinoma: Making ultrasonography more meaningful


Rahul Gandhi1, Abhishek Singh Nayyar1, Rahul Bhowate2, Sweta Gandhi3, Girish Dongerwar2 
1 Department of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital, Post-Graduate Research Institute, Parbhani, India
2 Department of Oral Medicine and Radiology, Sharad Pawar Dental College and Hospital, Wardha, India
3 Department of Public Health Dentistry, Lata Mangeshkar Dental College and Hospital, Nagpur, Maharashtra, India

Correspondence Address:
Abhishek Singh Nayyar
518-R, Model Town, Panipat - 132 103, Haryana, India.
India

Background: Although color Doppler ultrasonography (CD-USG) is useful in the diagnosis of various diseases of the head and neck, flow signals in the malignant oral tumors are less studied; hence, the present study was designed to study the usefulness of CD-USG in quantifying oral squamous cell carcinoma (OSCC) vascularization and in determining the hemodynamic parameters by spectral analysis obtained during CD-USG procedure. Aims: To study the usefulness of CD-USG in mapping OSCC of buccal mucosa, tongue, and lip. Materials and Methods: This was a case-control study, conducted among 60 subjects aged 20–70 years. Group A consisted of 30 cases of OSCC of buccal mucosa, tongue, and lip while Group B consisted of 30 controls. CD-USG investigation of each mass was carried out. The spectral waveform (time-velocity Doppler spectrum) of flow signal was analyzed for the pulsatility index, resistivity index (RI), peak systolic velocity (PSV) (m/s), and end diastolic velocity (EDV) (m/s). All patients had real-time, gray-scale sonography and CD-USG with spectral wave analysis. Results: In this study, the mean value for RI in patients with malignancy was 0.40 ± 0.14 whereas for healthy subjects, it was 0.83 ± 0.07. Mean value for PI in patients with malignancy was 0.86 ± 0.20 whereas for healthy subjects, it was 2.61 ± 0.77. In the present study, the mean PSV in malignant masses was 31.72 ± 13.48 whereas for healthy subjects, it was 43.87 ± 20.95, and the EDV in malignant masses was 10.33 ± 5.21 whereas for healthy subjects, it was 7.07 ± 3.44. Conclusion: The said Doppler indices were shown to be sensitive as well as specific for the diagnosis of malignant oral tumors. Although CD-USG cannot replace histopathological procedures, it plays a definite role as an adjunct to the clinical evaluation of OSCC cases.


How to cite this article:
Gandhi R, Nayyar AS, Bhowate R, Gandhi S, Dongerwar G. Color Doppler ultrasonography in oral squamous cell carcinoma: Making ultrasonography more meaningful.Clin Cancer Investig J 2015;4:595-602


How to cite this URL:
Gandhi R, Nayyar AS, Bhowate R, Gandhi S, Dongerwar G. Color Doppler ultrasonography in oral squamous cell carcinoma: Making ultrasonography more meaningful. Clin Cancer Investig J [serial online] 2015 [cited 2021 Apr 21 ];4:595-602
Available from: https://www.ccij-online.org/article.asp?issn=2278-0513;year=2015;volume=4;issue=5;spage=595;epage=602;aulast=Gandhi;type=0