| CASE REPORT |
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| Year : 2019 | Volume
: 8
| Issue : 6 | Page : 257-260 |
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Squash cytology of langerhans cell histiocytosis of sellar region
Supriya Verma, Parinitha S Sangam, Ravikala V Rao
Department of Pathology, Shri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital, Sattur, Dharwad, Karnataka, India
Correspondence Address:
Supriya Verma
Officers' Mess, MH Shimla, Jutogh Cantt, Shimla - 171 008, Himachal Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ccij.ccij_66_19
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Langerhans cell histiocytosis (LCH) is a systemic disease, which usually involves the skeleton and skin of children with occasional involvement of the central nervous system (hypothalamo–pituitary axis). We report the case of a 16-year-old male with a space-occupying lesion (SOL) in the sellar region and diabetes insipidus. However, no systemic abnormality was noted. A clinical diagnosis of pituitary adenoma was given. However, on intraoperative consultation by squash smears, cells with nuclear grooves and few eosinophils were seen. Hence, a differential diagnosis of LCH was also given, which was confirmed by histopathology and immunohistochemistry. Hence, as a matter of fact, LCH should be considered as one of the rare differential diagnoses of SOL of sellar region.
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