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  Indian J Med Microbiol
 

Figure 4: MD-HCC: Fine-needle aspiration cytology: (a) Large clusters of malignant hepatocytes show a vague trabecular pattern with many dispersed atypical nuclei (PAP, ×100). (b) Hepatocytes show a high N:C ratio, large nuclei, multi-nucleation, macronucleoli and golden yellow bile thrombi. The inset figure shows a large intranuclear inclusion (PAP, ×400). Fine-needle aspiration biopsy: (c) Pleomorphic hepatocytes show multi-nucleation, prominent nucleoli, intranuclear inclusions and a focal area of cytoplasmic clearing (H and E, ×400)

Figure 4: MD-HCC: Fine-needle aspiration cytology: (a) Large clusters of malignant hepatocytes show a vague trabecular pattern with many dispersed atypical nuclei (PAP, ×100). (b) Hepatocytes show a high N:C ratio, large nuclei, multi-nucleation, macronucleoli and golden yellow bile thrombi. The inset figure shows a large intranuclear inclusion (PAP, ×400). Fine-needle aspiration biopsy: (c) Pleomorphic hepatocytes show multi-nucleation, prominent nucleoli, intranuclear inclusions and a focal area of cytoplasmic clearing (H and E, ×400)