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  Indian J Med Microbiol
 

Figure 3: WD-HCC: Fine-needle aspiration cytology: (a) High cellularity with large clusters of hepatocytes and many bare atypical nuclei (H and E, ×100). (b) Polygonal hepatocytes show increased nucleus-to-cytoplasmic (N:C) ratio, rounded nuclei, abundant granular eosinophilic cytoplasm and intracytoplasmic bile; cluster of malignant cells traversed by spindle endothelial cells (H and E, ×400). Fine-needle aspiration biopsy: (c) Hepatocytes show central nuclei, prominent nucleoli and granular cytoplasm; cells show a predominant trabecular pattern with occasional acinar configuration (H and E, ×400)

Figure 3: WD-HCC: Fine-needle aspiration cytology: (a) High cellularity with large clusters of hepatocytes and many bare atypical nuclei (H and E, ×100). (b) Polygonal hepatocytes show increased nucleus-to-cytoplasmic (N:C) ratio, rounded nuclei, abundant granular eosinophilic cytoplasm and intracytoplasmic bile; cluster of malignant cells traversed by spindle endothelial cells (H and E, ×400). Fine-needle aspiration biopsy: (c) Hepatocytes show central nuclei, prominent nucleoli and granular cytoplasm; cells show a predominant trabecular pattern with occasional acinar configuration (H and E, ×400)