A case series of extremely rare and unusual cases of intracranial hemangiopericytoma: An institutional experience

We report a case series of three extremely rare and unusual cases of intracranial hemangiopericytoma diagnosed and treated in our institute, scarcely reported in world literature until date. These are highly aggressive and uncommon tumors accounting for <1% of all intracranial neoplasms, arising from Zimmerman's pericytes around capillaries and postcapillary venules. First two patients presented in 2011 and 2012 and were diagnosed as hemangiopericytoma Grade II with vimentin and CD34 positivity on immunohistochemistry. In 2014, a third patient was diagnosed as an anaplastic Grade III tumor, positive for vimentin and negative for epithelial membrane antigen. All three patients were treated with adjuvant radiotherapy to the brain and were kept on follow-up. However, the first patient recurred after 5 years for which he underwent redo-surgery. Other two patients are on follow-up with no evidence of recurrence or distant metastasis.