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An official publication of the Middle-Eastern Association for Cancer Research
Clinical Cancer Investigation Journal
ISSN Print: 2278-1668, Online: 2278-0513
ARTICLE
Year: 2015   |   Volume: 4   |   Issue: 3   |   Page: 435-437     View issue

Retinal detachment as the inaugural manifestation in Waldenstrom′s macroglobulinemia


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Abstract

Waldenstrom′s macroglobulinemia (WM) is a rare disorder and forms 1-2% of hematological malignancies. Rarely retinal detachment precedes the diagnosis of WM. In this case report, we present 65-year-old man with retinal detachment as the inaugural manifestation in WM. Clinical manifestations in WM are related to direct tumor infiltration, circulating immunoglobulin M (IgM) and deposition into tissues, amyloidogenic properties and autoantibody activity of IgM. Diagnosis is difficult, when a rare disease manifests differently, as in our case. Delay in diagnosis can be prevented by heightened awareness of this rare disease.

Cite this article
Vancouver
Raghavendra H, Rajkumar N, Chinnagiriyappa L, Devi V. Retinal detachment as the inaugural manifestation in Waldenstrom′s macroglobulinemia. Clin Cancer Investig J. 2015;4(3):435-7. https://doi.org/10.4103/2278-0513.154536
APA
Raghavendra, H., Rajkumar, N., Chinnagiriyappa, L., & Devi, V. (2015). Retinal detachment as the inaugural manifestation in Waldenstrom′s macroglobulinemia. Clinical Cancer Investigation Journal, 4(3), 435-437. https://doi.org/10.4103/2278-0513.154536

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ISSN Print: 2278-1668, Online: 2278-0513