Clinical Cancer Investigation Journal

CASE REPORT
Year
: 2019  |  Volume : 8  |  Issue : 6  |  Page : 257--260

Squash cytology of langerhans cell histiocytosis of sellar region


Supriya Verma, Parinitha S Sangam, Ravikala V Rao 
 Department of Pathology, Shri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital, Sattur, Dharwad, Karnataka, India

Correspondence Address:
Supriya Verma
Officers' Mess, MH Shimla, Jutogh Cantt, Shimla - 171 008, Himachal Pradesh
India

Langerhans cell histiocytosis (LCH) is a systemic disease, which usually involves the skeleton and skin of children with occasional involvement of the central nervous system (hypothalamo–pituitary axis). We report the case of a 16-year-old male with a space-occupying lesion (SOL) in the sellar region and diabetes insipidus. However, no systemic abnormality was noted. A clinical diagnosis of pituitary adenoma was given. However, on intraoperative consultation by squash smears, cells with nuclear grooves and few eosinophils were seen. Hence, a differential diagnosis of LCH was also given, which was confirmed by histopathology and immunohistochemistry. Hence, as a matter of fact, LCH should be considered as one of the rare differential diagnoses of SOL of sellar region.


How to cite this article:
Verma S, Sangam PS, Rao RV. Squash cytology of langerhans cell histiocytosis of sellar region.Clin Cancer Investig J 2019;8:257-260


How to cite this URL:
Verma S, Sangam PS, Rao RV. Squash cytology of langerhans cell histiocytosis of sellar region. Clin Cancer Investig J [serial online] 2019 [cited 2020 Feb 28 ];8:257-260
Available from: http://www.ccij-online.org/article.asp?issn=2278-0513;year=2019;volume=8;issue=6;spage=257;epage=260;aulast=Verma;type=0