Clinical Cancer Investigation Journal

REVIEW ARTICLE
Year
: 2013  |  Volume : 2  |  Issue : 2  |  Page : 101--105

Myoepithelial cells: Current perspectives in salivary gland tumors


C Pramod Redder1, V Suresh Kandagal1, Nupura Vibhute1, Pramod S Ingaleshwar2, Sharan J Shetty2, Sameer Ahamad3 
1 Department of Oral Pathology and Microbiology, School of Dental Sciences, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India
2 Department of Oral Pathology and Microbiology, A. J. Institute of Dental Sciences, Mangalore, Karnataka, India
3 Department of Oral Pathology and Microbiology, Kunhitharuvai Memorial Charitable Trust Dental College, Calicut, Kerala, India

Correspondence Address:
V Suresh Kandagal
Department of Oral Medicine and Radiology, School of Dental Sciences, Krishna Institute of Medical Sciences University, Karad, Satara, Maharashtra
India

Myoepithelial cells are normal constituent of the salivary acini and smaller ducts, and are found between the epithelial cells and the basement membrane. Microscopic examination shows that myoepithelial cells are thin and spindle-shaped and situated between the basement membrane and epithelial cells. Ultrastructurally they possess a number of cytoplasmic processes that extend between and over the acinar and ductal-lining cells. They display features of both smooth muscle and epithelium, such as numerous microfilaments with focal densities in the cytoplasmic processes, and desmosomes which attach the myoepithelial to the epithelial cells. Neoplastic myoepithelial cells in both benign and malignant tumors can take several forms, including epithelioid, spindle, plasmacytoid, and clear, and this variability largely accounts for difficulties in histopathological diagnosis. This review article highlights the role of myoepithelial cells in salivary gland tumors.


How to cite this article:
Redder C P, Kandagal V S, Vibhute N, Ingaleshwar PS, Shetty SJ, Ahamad S. Myoepithelial cells: Current perspectives in salivary gland tumors.Clin Cancer Investig J 2013;2:101-105


How to cite this URL:
Redder C P, Kandagal V S, Vibhute N, Ingaleshwar PS, Shetty SJ, Ahamad S. Myoepithelial cells: Current perspectives in salivary gland tumors. Clin Cancer Investig J [serial online] 2013 [cited 2019 Sep 22 ];2:101-105
Available from: http://www.ccij-online.org/article.asp?issn=2278-0513;year=2013;volume=2;issue=2;spage=101;epage=105;aulast=Redder;type=0