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Year : 2019  |  Volume : 8  |  Issue : 4  |  Page : 139-143

Immunotherapy in breast cancer


1 Department of Hematology and Medical Oncology, Shaheed Modarres Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
2 Department of Biology, Zanjan Branch, Islamic Azad University, Zanjan, Iran
3 Department of Cellular-Molecular Biology, Faculty of Biological Sciences and Technologies, Shahid Beheshti University, Tehran, Iran
4 Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
5 Department of Medical Genetics, Cancer Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6 Department of Mycobacteriology and Pulmonary Research, Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran

Correspondence Address:
Abolfazl Movafagh
Department of Medical Genetics, Cancer Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ccij.ccij_45_19

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Over the last few years, the developments around cancer immunotherapy have led to a paradigm shift in the treatment of many different cancers and leukemias, in particular, melanoma, renal, bladder, and lung cancers with a remarkable impact on response rate and most importantly, overall survival was noticed. Breast cancer is most commonly considered to be a “noninflamed” cancer, and hence, this shift has been less marked within its treatment. However, some subsets of breast cancer, most notably triple-negative breast cancer, are deemed to be more “inflamed” and therefore may prove to be an appropriate cohort for immunotherapy.


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