Submit Your Article CMED MEACR meeting
Home Print this page Email this page Users Online: 237
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2016  |  Volume : 5  |  Issue : 5  |  Page : 384-387

The predictive role of thrombocytosis in identifying patients with advanced lung carcinoma in an urban medical center


1 Internal Medicine, Pulmonary and Hematology and Oncology Department, Saint Michael's Medical Center, Newark, New Jersey, USA
2 Hematology and Oncology, Saint Michael's Medical Center, Newark, New Jersey, USA

Correspondence Address:
Hamid Shaaban
Department of Hematology and Oncology, Saint Michael's Medical Center, Newark, New Jersey
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-0513.197877

Rights and Permissions

Study Objectives: Lung carcinoma is leading cause of death from cancer, thus an important subject for review. Lung carcinoma is associated with various prognostic factors including both clinical and objective findings; therefore, a review of thrombocytosis regarding predicting stage at initial diagnosis was prompted. Materials and Methods: A retrospective chart review of 180 patients diagnosed with lung carcinoma at Saint Michael's Medical Center between 2009 and 2013 and comparison with platelet level at time of diagnosis. The pathological diagnosis of lung cancer was made by either trans-bronchial or CT guided biopsy. Design: A retrospective chart review of 180 patients diagnosed with lung carcinoma at Saint Michael's Medical Center between 2009 and 2013 and comparison with platelet level at time of diagnosis. Results: No statistical significance was determined between advanced (including advanced staging of small cell lung cancer [SCLC] and Stage IIIb-IV of non-SCLC [NSCLC]) lung cancer staging and elevated platelet level (P = 0.078 and confidence interval [CI] of −89.103–4.774). However, on a subgroup analysis of cases including only NSCLC showed a statistically significant difference between limited and advanced stages (P = 0.0.18 and CI of −95.756–9.104). Conclusions: Thrombocytosis is associated with various neoplasms, included lung cancer as indicated in this retrospective study. In fact, thrombocytosis has been implicated with advanced staging of both SCLC and NSCLC, therefore indicating poor outcomes and mortality.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1324    
    Printed21    
    Emailed0    
    PDF Downloaded15    
    Comments [Add]    

Recommend this journal