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Year : 2015  |  Volume : 4  |  Issue : 3  |  Page : 387-390

Plasmablastic lymphoma of the testis in a human immunodeficienecy virus patient - report of a rare entity

Department of Pathology, R.D.T. Hospital, Bathalapalli, Andhra Pradesh, India

Correspondence Address:
Nandyala Hariharanadha Sarma
Department of Pathology, R.D.T. Hospital, Bathalapalli - 515 661, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-0513.151944

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Testicular lymphoma is the second most common extra nodal lymphomas. It is a highly lethal disease with a median survival of 1-2 years. In human immunodeficiency virus (HIV) patients, primary testicular lymphomas are estimated to comprise > 6% of testicular tumors, and they tend to occur in younger patients. Testicular lymphoma can occasionally be the initial manifestation of the disease in HIV patients.Plasmablastic lymphoma (PBL), which is considered as a variant of diffuse large B-cell lymphoma is a highly aggressive tumor with poor prognosis. PBL has a well-established association with HIV infection and occurs most commonly in the oral cavity. The presentation at extra nodal sites and absence of usual hematolymphoid markers makes its diagnosis more difficult. PBL of the testis as the primary lesion in HIV patients has not been reported so far. We report a case of PBL presenting as a primary testicular lesion in a HIV patient with a grave prognosis.

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