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Year : 2015  |  Volume : 4  |  Issue : 1  |  Page : 43-46

Lesion of Dual Nature - Carcinoma or Sarcoma: A Histopathologic Dilemma

1 Department of Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Sawangi (M), Wardha, Maharashtra, India
2 Department of Oral and Maxillofacial Surgery, Sharad Pawar Dental College and Hospital, Sawangi (M), Wardha, Maharashtra, India

Correspondence Address:
Shree Kanhaiya Bajaj
Department of Oral Pathology and Microbiology, Room No 107, First Floor, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Sawangi (M), Wardha, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-0513.149038

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Sarcomatoid carcinomas are biphasic tumors proven to be monoclonal dedifferentiated forms of conventional squamous carcinomas. It is a variant of squamous cell carcinoma (SCC) which has spindled tumor cells, which simulate a true sarcoma, but are epithelial in origin. They are extremely uncommon in the head and neck region. Only 10 cases have been discussed in the literature. When compared to SCC of maxilla, this variant is associated with poor diagnosis and advanced disease at presentation as is demonstrated in the case presented. Diagnosis of sarcomatoid squamous carcinoma is challenging because of overlapping histopathological features with other spindle-cell tumors. Understanding their clinicopathologic characteristics facilitates their diagnosis and appropriate clinical management. Surgery and radiotherapy form the mainstays of treatment. We report a rare case of spindle-cell carcinoma involving the mandible.

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