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REVIEW ARTICLE
Year : 2014  |  Volume : 3  |  Issue : 3  |  Page : 196-199

Post-operative adjuvant treatment in carcinoma gall bladder: A brief review


1 Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Pramod Kumar Singh
Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-0513.132108

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Gallbladder cancer (GBC) represents the most common malignancy among the biliary tree cancers representing 3% of such tumors. Complete surgical resection offers the best chance for cure. Adjuvant chemotherapy and radiotherapy are less well-defined and need to be further evaluated to increase local and systemic control. Local recurrences as high as 75% have been reported after radical cholecystectomy in GBC. The patterns of failure and poor overall prognosis in GBC, justify administration of adjuvant treatments. Only an estimated 20% of patients receive radiotherapy or chemotherapy after resection and fewer than 10% of all presenting patients undergo surgery, radiotherapy and chemotherapy. Recent series have suggested that local-regional control and possibly ultimate outcome can be improved by the use of adjuvant therapy.


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