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Year : 2013  |  Volume : 2  |  Issue : 1  |  Page : 60-62

Rectal adenocarcinoma with extensive choriocarcinomatous differentiation: Report of a rare occurrence

1 Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
2 Pgy3, Internal Medicine Resident, John H Stroger Hospital of Cook County, Chicago, IL, USA

Correspondence Address:
Kavita Mardi
12-A, Type V Quarters, IAS Colony, Kasumpti, Shimla, Himachal Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-0513.110790

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We report a rare case of choriocarcinomatous differentiation of tumor cells in the rectal adenocarcinoma of a 54-year-old female who presented with pain abdomen and passage of bloody stools. CT scan was suggestive of a malignant tumor in the rectum. Histologic examination of the tumor revealed a minor component of moderately differentiated adenocarcinoma that showed extensive trophoblastic differentiation. Positive immunostaining for beta-hCG of tumor cells in these areas confirmed the diagnosis. Since such tumors behave aggressively and confer bad prognosis, they constitute a distinct clinical entity of a gastrointestinal tumor.

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