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ORIGINAL ARTICLE
Year : 2012  |  Volume : 1  |  Issue : 1  |  Page : 23-25

Helicobacter pylori in colorectal neoplasms of Kashmiri patients: What is the prevalence?


1 Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences, Soura; Department of Biochemistry, Medical College, Sher-I-Kashmir Institute of Medical Sciences, Bemina, Srinagar, Kashmir, India
2 Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir, India

Correspondence Address:
Aga Syed Sameer
Department of Biochemistry, Medical College, Sher-I-Kashmir Institute of Medical Sciences, Bemina, Srinagar, Kashmir
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-0513.95015

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Background: The purpose of the present study was to detect the presence of Helicobacter pylori in colorectal cancer (CRC) patients in Kashmiri population. Materials and Methods: A total of 86 CRC samples were studied. Samples were taken from tissues suitable for DNA amplification by polymerase chain reaction (PCR). DNA was extracted and H. pylori detection was carried out by PCR amplification of glmM gene. Results: Out of 86 samples, only eight were H. pylori-positive for amplification glmM gene of a 294 bp DNA fragment. Conclusion: H. pylori is not the prominent risk factor for the development of colorectal cancer in Kashmiri population.


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